Publications:
Horn, A.V., Celic, I., Dong, C., Martirosyan, I., and Han, J.S. A conserved role for the ESCRT membrane budding complex in LINE retrotransposition. PLOS Genetics (2017) 13:e1006837
Horn, A.V. and Han, J.S. LINE retrotransposition assays in Saccharomyces cerevisiae. Methods Mol Biol (2016) 1400:131-137.
Annaluru, N., Muller,H., Mitchell, L.A., Ramalingam, S.,Stracquadanio, G., Richardson, S.M., Dymond, J.S., Scheifele, L.Z., Cooper, E.M.,Cai, Y., Zeller, K., Agmon, N., Han, J.S., Hadjithomas, M., Tullman, J., Caravelli, K., Cirelli, K., Guo, Z., London, V., Yeluru, A., Murugan, S., Kandavelou, K., Yang, K., Martin, J.A., Bilgel, M., Bohutski, P., Boulier, K.M., Capalso, B.J., Chang, J., Charoen, K., Choi, W.J., Deng, P., DiCarlo, J.E., Doong, J., Dunn, J., Feinberg, J.I., Fernandez, C., Floria, C.E., Gladowski, D., Hadidi, P., Ishizuka, I., Jabbari, J., Lau, C., Lee, P.A., Li, S., Lin, D., Linder, M.E., Ling, J., Liu, J., Liu, J., London, M., Ma, H., Mao, J., McDade, J.E., McMillan, A., Moore, A.M., Oh, W.C., Ouyang, C., Patel, R., Paul, M., Paulsen, L.C., Qiu, J., Rhee, A., Rubashkin, M.G., Soh, I.Y., Sotuyo, N.E., Srinivas, V., Suarez, A., Wong, A., Wong, R., Xie, W.R., Xu, Y., Yu, A.T., Koszul, R., Bader, J.S., Boeke, J.D., and Chandraswgaran, S. Total synthesis of a Functional Designer Eukaryotic Chromosome. Science (2014) 344:55-58.
Horn, A.V. Klawitter, S., Held, U., Berger, A., Jaguva Vasudevan, A.A., Bock, A., Hofmann, H., Hanschmann, K.M., Trosemeier, J.H., Flory, E., Jabulowsky, R.A., Han, J.S., Lower, J., Lower, R., Munk, C., and Schumann, G.G. Human LINE-1 restriction by APOBEC3C is deaminase independent and mediated by an ORF1p interaction that affects LINE reverse transcriptase activity. Nucleic Acids Research (2014) 42:396-416.
Han, J.S., and Shao, S. Circular retrotransposition products generated by a LINE retrotransposon. Nucleic Acids Research (2012) 40:10866. *Featured Article
An, W., Dai, L., Niewiadomska, A.M., Yetil, A., O’Donnell, K.A., Han, J.S., and Boeke, J.D. Characterization of a synthetic human LINE-1 retrotransposon ORFeus-Hs. Mob DNA (2011) 2:2.
Han, J.S. Non-long terminal repeat (non-LTR) retrotransposons: mechanisms, recent developments, and unanswered questions. Mob DNA (2010) 1:15.
Dong, C, Poulter, R.T., Han, J.S. LINE-like Retrotransposition in Saccharomyces cerevisiae. Genetics (2009) 181, 301-311. *Issue Highlights
An, W., Han, J.S., Schrum, C.M., Maitra, A., Koentgen, F., and Boeke, J.D. Controlled activation of a single-copy L1 transgene in mice by Cre recombinase. Genesis (2008) 46, 373-383.
Boeke, J.D., An, W., Dai, L., Davis, E.S., Han, J.S., O’Donnell, K.A., Scheifele, L.Z., and Wheelan, S.J. Retrotransposons – natural and synthetic. In Retrotransposition, Diversity and the Brain (eds. Gage, F.H. & Christen, Y.) 21-32 (Springer-Verlag Berlin Heidelberg, 2007).
An, W., Han, J.S., Wheelan, S.J., Davis, E.S., Coombes, C.E., Ye, P., Triplett, C., and Boeke, J.D. Active retrotransposition by a synthetic L1 element in mice. Proc Natl Acad Sci USA (2006) 103:18662-18667.
Wheelan, S.J., Aizawa, Y., Han, J.S., and Boeke, J.D. Gene-breaking: a new paradigm for human retrotransposon-mediated gene evolution. Genome Research (2005) 15, 1073-1078.
Han, J.S., and Boeke, J.D. LINE-1 retrotransposons: modulators of quantity and quality of mammalian gene expression? Bioessays (2005) 27, 775-784.
Han Laboratory
Tulane Cancer Center
1700 Tulane Avenue
LCRC Room 743
New Orleans, LA 70112